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The magnitude and significance of drug interactions are difficult to predict when several drugs with competing metabolic pathways are prescribed concomitantly. In Viagra 50mg where an interacting drug needs to be replaced with an alternative, providers should exercise their reasons of ED judgement to select the most appropriate alternative medication to use. The information in the brief version is excerpted directly from the full-text guidelines.

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Itraconazole is predicted to increase the exposure to vinblastine. Both itraconazole and vincristine can increase the risk of hepatotoxicity.